Products
SLC11A2 antibody
- Product Name
- SLC11A2 antibody
- Catalogue No.
- FNab07905
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- solute carrier family 11(proton-coupled divalent metal ion transporters), member 2
- Alternative Names
- DCT1 antibody, DMT1 antibody, NRAMP2 antibody
- UniProt ID
- P49281
- Observed MW
- 60-70, 75-100 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab07905(SLC11A2 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded mouse stomach using FNab07905(SLC11A2 antibody) at dilution of 1:50
- Background
- Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
